Natural products of Alternaria sp., an endophytic fungus isolated from Salvadora persica from Saudi Arabia
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چکیده
منابع مشابه
Altenusin, a biphenyl isolated from the endophytic fungus Alternaria sp., inhibits trypanothione reductase from Trypanosoma cruzi.
Parasitic protozoan species belonging to the genera Trypanosoma and Leishmania are the etiological agents of several diseases in tropical areas of the world, for which there is an urgent need for effective and affordable treatment. In this regard, we are screening the Brazilian biodiversity, especially its flora and mycota, for natural products that could serve as leads for drug development aga...
متن کاملChemical and bioactive natural products from Microthyriaceae sp., an endophytic fungus from a tropical grass.
UNLABELLED In screening for natural products with antiparasitic activity, an endophytic fungus, strain F2611, isolated from above-ground tissue of the tropical grass Paspalum conjugatum (Poaceae) in Panama, was chosen for bioactive principle elucidation. Cultivation on malt extract agar (MEA) followed by bioassay-guided chromatographic fractionation of the extract led to the isolation of the ne...
متن کاملAn endophytic fungus isolated from finger millet (Eleusine coracana) produces anti-fungal natural products
Finger millet is an ancient African cereal crop, domesticated 7000 years ago in Ethiopia, reaching India at 3000 BC. Finger millet is reported to be resistant to various fungal pathogens including Fusarium sp. We hypothesized that finger millet may host beneficial endophytes (plant-colonizing microbes) that contribute to the antifungal activity. Here we report the first isolation of endophyte(s...
متن کاملAntifungal activity of altenusin isolated from the endophytic fungus Alternaria sp. against the pathogenic fungus Paracoccidioides brasiliensis.
BACKGROUND Altenusin is a biphenyl derivative isolated from different species of fungi, which presents several biological activities. AIMS We report the antifungal activity of the altenusin isolated from the endophytic fungus Alternaria sp., against clinical isolates of Paracoccidioides brasiliensis, and its action on cell walls of P. brasiliensis and the nonpathogenic yeast Schizosaccharomyc...
متن کاملTwo New Metabolites from the Endophytic Fungus Alternaria sp. A744 Derived from Morinda officinalis.
Two new compounds isobenzofuranone A (1) and indandione B (2), together with eleven known compounds (3-13) were isolated from liquid cultures of an endophytic fungus Alternaria sp., which was obtained from the medicinal plant Morinda officinalis. Among them, the indandione (2) showed a rarely occurring indanone skeleton in natural products. Their structures were elucidated mainly on the basis o...
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ژورنال
عنوان ژورنال: Saudi Journal of Biological Sciences
سال: 2019
ISSN: 1319-562X
DOI: 10.1016/j.sjbs.2018.04.010